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甾體化合物報(bào)價(jià)

2021/2/26 17:13:19  作者:騰準(zhǔn)&思域


 

類固醇激素是一類脂溶性激素,它們?cè)诮Y(jié)構(gòu)上都是環(huán)戊烷多氫菲衍生物。即甾烷類化合物,類固醇激素是一類脂溶性激素,它們?cè)诮Y(jié)構(gòu)上都是環(huán)戊烷多氫菲衍生物。脊椎動(dòng)物的腎上腺激素可分為腎上腺皮質(zhì)激素和性激素兩類。

     (1) 皮質(zhì)激素進(jìn)入血液循環(huán)后,一般與血中特異的蛋白質(zhì)——皮質(zhì)激素運(yùn)載蛋白形成可逆的非共價(jià)鍵復(fù)合物,使激素免受破壞,并可調(diào)節(jié)血中游離甾體的濃度,從而調(diào)控作用于靶細(xì)胞的激素的有效濃度。根據(jù)目前通行的假說,進(jìn)入細(xì)胞的皮質(zhì)激素也如其他甾體激素一樣,與細(xì)胞內(nèi)特異受體相結(jié)合,經(jīng)激活后結(jié)合細(xì)胞核,影響染色質(zhì)的轉(zhuǎn)錄作用,誘導(dǎo)新的蛋白質(zhì)合成,表現(xiàn)為細(xì)胞功能的變化。皮質(zhì)激素按其生理功能可分為糖皮質(zhì)激素及鹽皮質(zhì)激素兩類。

       糖皮質(zhì)激素(Glucocorticoid),又名“腎上腺皮質(zhì)激素”,是由腎上腺皮質(zhì)分泌的一類甾體激素,也可由化學(xué)方法人工合成。由于可用于一般的抗生素或消炎藥所不及的病癥,如SARS、敗血癥等,具有調(diào)節(jié)糖、脂肪、和蛋白質(zhì)的生物合成和代謝的作用,還具有抗炎作用,稱其為“糖皮質(zhì)激素”是因?yàn)槠湔{(diào)節(jié)糖類代謝的活性最早為人們所認(rèn)識(shí)。

 

      鹽皮質(zhì)激素(mineralocorticoid)是由腎上腺皮質(zhì)球狀帶細(xì)胞分泌的類固醇激素,主要生理作用是維持人體內(nèi)水和電解質(zhì)的平衡。

   (2)性激素。性激素屬于類固醇類激素,可分為雄性激素和雌性激素兩類。它們與動(dòng)物的性別及第二性征的發(fā)育有關(guān)。性激素的分泌受腦垂體的促性腺激素調(diào)節(jié)。

 

試劑列表

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E830039 15140-27-9 環(huán)己甲酸雌二醇, 98%  estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate, 98% C25H34O3 購買
E830035 113-38-2 二丙酸雌二醇, 98%  17-β-ESTRADIOL 3,17-DIPROPIONATE, 98% C24H32O4 購買
C830031 5749-67-7 卡巴匹林鈣, 98%   Carbasalate calcium, 98% C18H14CaO8.CH4N2O 購買
P829930 50-24-8 潑尼松龍, 98%  Prednisolone, 98% C21H28O5 購買
H829988 68-96-2 羥孕酮, 98%  17α-Hydroxyprogesterone, 98% C21H30O3 購買
R829991 51372-29-3 布地奈德, 98%  (22R)-Budesonide, 98% C25H34O6 購買
D829998 55203-24-2 地塞米松磷酸鈉, 98%  Dexamethasone sodium phosphate, 98% C22H28FNa2O8P 購買
H830005 630-56-8 己酸孕酮, 98%  17a-Hydroxyprogesterone caproate, 98% C27H40O4 購買
A830043 95716-70-4 孕烯羧酸內(nèi)酯, 98%  (7a,17a)-17-羥基-3-氧代-孕甾-4,9(11)-二烯-7,21-二羧酸 gamma-內(nèi)酯甲酯, 98% C24H30O5 購買
E830044 96937-85-8 黃體酮羧酸甲酯, 98%  Estr-?4-?ene-?17-?carboxylic acid, 3-?oxo-?, methyl ester, (17β)?- (9CI), 98% C21H30O3 購買
D830008 56-47-3 乙酸去氧皮質(zhì)酮, 98%  3,20-Dioxopregn-4-en-21-yl acetate, 98% C23H32O4 購買
S830011 1099-87-2 去氫表雄酮硫酸鈉, 98%  Sodium prasterone sulfate, 98% C19H27NaO5S 購買
T830020 5949-44-0 十一酸睪丸素, 98%  Testosterone undecanoate, 98% C30H48O3 購買
C830017 54063-32-0 氯倍他松, 98%  Clobetasone, 98% C22H26ClFO4 購買
H830021 13609-67-1 丁酸氫化可的松, 98%  Hydrocortisone-17-butyrate, 98% C25H36O6 購買
F830023 33124-50-4 氟可丁, 98%  fluocortin, 98% C22H27FO5 購買
A830025 2119-75-7 氟培龍, 98%  Alacortril, 98% C24H31FO6 購買
F829928 426-13-1 氟米龍, 98%  Fluorometholone, 98% C22H29FO4 購買
F829927 2193-87-5 氟潑尼定, 98%  fluprednidene, 98% C22H27FO5 購買
V830026 67452-97-5 阿氯米松, 98%  Vaderm, 98% C22H29ClO5 購買
H830027 72590-77-3 丙丁酸氫化可的松, 98%  Hydrocortisone butyrate propionate, 98% C28H40O7 購買
C830028 4828-27-7 氯可托龍, 98%  Clocortolone, 98% C22H28ClFO4 購買
F830029 3693-39-8 氟氯洛龍, 98%  fluclorolone acetonide, 98% C24H29Cl2FO5 購買
F829985 356-12-7 醋酸氟輕松, 98%  Fluocinonide, 98% C26H32F2O7 購買
F829993 152-97-6 氟可龍, 98%  Fluocortolone, 98% C22H29FO4 購買
F829996 1524-88-5 氟氫縮松, 98%  Fludroxycortide, 98% C24H33FO6 購買
A829977 51022-69-6 安西奈德, 98%  Amcinonide, 98% C28H35FO7 購買
H829975 50629-82-8 鹵米松, 98%  Halometasone, 98% C22H27ClF2O5 購買
M829974 86401-95-8 甲基潑尼松龍乙丙酸酯, 98%  Methylprednisolone aceponate, 98% C27H36O7 購買
B829967 4419-39-0 甲醇中倍氯米松, 98%  Beclomethasone, 98% C22H29ClO5 購買
H829971 74050-20-7 醋丙氫可的松, 98%  Hydrocortisone, 98% C26H36O7 購買
F829964 90566-53-3 氟替卡松, 98%  Fluticasone, 98% C25H31F3O5S 購買
P829950 73771-04-7 潑尼卡酯, 98%  Prednicarbate, 98% C27H36O8 購買
D829966 23674-86-4 二氟孕甾丁酯, 98%  Difluprednate, 98% C27H34F2O7 購買
U830001 98651-66-2 鹵倍他松, 98%  Ulobetasol, 98% C22H27ClF2O4 購買
R829937 76675-97-3 瑞索可托, 98%  Resocortol, 98% C22H32O4 購買
C829932 25122-41-2 氯倍他索, 98%  Clobetasol, 98% C22H28ClFO4 購買
H829934 3093-35-4 哈西奈德, 98%  Halcinonide, 98% C24H32ClFO5 購買
M830013 83-43-2 甲基潑尼松龍, 98%  6-α-Methylprednisolone, 98% C22H30O5 購買
M829922 105102-22-5 莫美他松, 98%  Mometasone, 98% C22H28Cl2O4 購買

 

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